Dioxins in pregnancy may affect the reproductive system of children

6 12 2012

Barcelona, 20 November of 2012.- The distances found, they are normally longer in boys than in girls, are reduced among newborn boys whose mothers had greater exposure to dioxins. As revealed in a study, directed by the Centre for research in environmental epidemiology (CREAL) Barcelona, you have participated 700 pregnant women and their newborns in Greece and Spain.

The researchers conclude that the anogenital distance, that is the distance between the anus and penis, was reduced by approximately half mm per each 10 picograms (1 picogram equals one trillionth part of a gram) of dioxin per gram of lipid measures. The Dra. Marina Vafeiadi, first author of the article, explains that “the distance anogenital is a sensitive marker to endocrine disruption and these small distances have been associated with hypospadias (a congenital defect of the urethra and penis), Cryptorchidism (Undescended Testicles) and also with a lower quality of semen and infertility in young men”. In fact, This study confirms human experimental evidence of the effects of dioxins in animals that already used the Organization United Nations food and agriculture (FAO) and the World Organization of the Bless you (WHO) to establish recommendations for Human intake of food dioxin.

Dioxin and similar compounds are persistent chemicals of by-products of industrial processes. The main sources of human exposure are foods rich in fat, mainly of animal origin such as meat, dairy products and fish. Dioxins are transmitted from mother to child through the placenta during pregnancy and after birth through breastfeeding.

The use of advanced biomedical techniques enabled the measurement of dioxin and similar compounds in the mother's blood using a test that provided an overall estimate of exposure to these compounds and the levels thereof during pregnancy.

According to the Coordinator of the study and joint scientific director of the CREAL, the Prof. Manolis Boada, “exposure to dioxins and related compounds has been significantly reduced in the industrialized countries in recent decades Thanks to the control measures. Our results indicate, However, efficient control of persistent compounds requires long periods of time to be effective. The study was conducted along with researchers from the University of Crete (Greece) and the Institute Hospital del Mar research medical-IMIM (Barcelona).

Reference article: In Utero Exposure to Dioxins and overwhelming-like Compounds and Anogenital Distance in Newborns and Infants. Environmental Health Perspectives.Marina Vafeiadi, Silvia Agramunt, Eleni Papadopoulou, Harrie Besselink, Kleopatra Mathianaki, Polyxeni Karakosta, Ariana Spanaki, Antonis Koutis, Leda Chatzi, Martine Vrijheid, Manolis Boada. http://dx.doi.org/10.1289/ehp.1205221.

For more information or arrange interviews, contact with: – Gisela Sanmartin, Head of communications at the CREAL: gsanmartin@creal.cat – View.: 93 214 73 33 – 696 912 841. www.creal.cat.


Creal.cat [en línea]Barcelona (ESP): creal.cat, 06 in December of 2012 [REF. 20 November of 2012] Available on Internet: http://www.creal.cat/noticies/view.php?ID = 229